<noscript id="kmmmi"></noscript>
  • <td id="kmmmi"><option id="kmmmi"></option></td>
    <td id="kmmmi"><option id="kmmmi"></option></td>
  • Service and cooperation

    Antibody Humanization

    Murine antibody can cause immunogenicity and reduced efficacy in human body. Antibody humanization can reduce the immunogenicity of murine monoclonal antibody. A common approach for humanization is complementary determining regions (CDR) grafting, in which 6 CDRs from a murine antibody are grafted onto a human antibody framework (FR). Some residues from the murine framework sequences need to be retained to replace the human residues at the corresponding positions (back mutations) in order to restore some of the lost affinity. Full-length IgG display libraries which containing FR/CDR variants are the best format to screen for binding properties in antibody humanization.

    Based on extensive experience and full-length IgG pichia display, Genekine provides premium quality service to generate humanized antibody. The humanized antibody has comparable binding affinity with parental antibody, and contains over 90% of human amino acid sequences.

     

    1. Antibody sequence and structure analysis;

    2. 3-D structural modeling;

    3. Construction and display of full-length IgG humanization library;

    4. FACS sorting to screen for IgG with high binding affinity and expression level. 


      Contact us

      0571-89059592

      Email:info@www.chinafkjx.com

      Add:Room 1001, Unit 6, Building 6, No. 1500, Wenyi West Road, Yuhang District, Hangzhou City, Zhejiang Province

    Follow us

    Hangzhou Jingyinkang Biological Technology Co., Ltd. | 浙ICP備15033920號 | Technical Support:REVAN

    Hangzhou Jingyinkang Biological Technology Co., Ltd.

    Follow us

    Online
    Tel

    0571-89059592

    国产成人久久综合碰碰,女人被狂c躁到高潮视频免费,白丝爆乳JK自慰流水网站,国产精品久久久久影院色老大
    <noscript id="kmmmi"></noscript>
  • <td id="kmmmi"><option id="kmmmi"></option></td>
    <td id="kmmmi"><option id="kmmmi"></option></td>